Vitamin B12 and Nervous System Function
Vitamin B12 (cobalamin) is a vital micronutrient essential for the proper functioning of the nervous system, blood formation, DNA synthesis, and energy production at the cellular level.
A deficiency in B12 has been linked to numerous neurological, psychiatric, and hematological disorders, particularly in at-risk populations such as the elderly, vegetarians, and individuals with gastrointestinal absorption issues.
🧠 Clinical Manifestations of B12 Deficiency
Scientific studies have associated vitamin B12 deficiency with:
- Peripheral neuropathies (numbness, weakness, loss of sensation)
- Cognitive decline and dementia (Selhub et al., 2002)
- Depression and mood disorders (Reynolds, 2006)
- Macrocytic anemia (Addison–Biermer disease) (Stabler, 2013)
Elevated homocysteine levels caused by impaired methionine metabolism—due to B12 deficiency—have also been linked to brain atrophy, cardiovascular risk, and mood disturbances.
🌞 B12 and the Sunlight Myth
Unlike vitamin D, which is synthesized in the skin via exposure to sunlight, vitamin B12 is not produced in the human body through sun exposure.
The only ways to acquire it are through diet and/or supplementation.
✅ Natural Sources of B12 Include:
- Meat (beef, pork, poultry)
- Fish (salmon, tuna, sardines)
- Shellfish
- Eggs
- Dairy products
- Fortified foods (e.g., cereals, plant-based milks — only if enriched with B12)
B12 is produced by bacteria — not by plants or animals — which is why plant-based foods naturally lack B12 unless fortified.
⚠ Signs of B12 Deficiency
According to peer-reviewed studies:
- Causes neurological symptoms: numbness, tingling, dizziness, poor balance
- Leads to cognitive impairment: “brain fog,” poor concentration, memory loss
- Associated with mood disorders: depression, irritability
- May cause macrocytic anemia
⚙ Biological Role of B12
Vitamin B12 plays a central role in two key enzymatic pathways:
- Methylcobalamin: Crucial for the synthesis of neurotransmitters like serotonin and norepinephrine
- Adenosylcobalamin: Supports the formation of succinyl-CoA, a compound essential for mitochondrial energy production and myelin maintenance
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MaxiHeal B12 Maxi Spray
The MaxiHeal B12 Maxi Spray provides an innovative and practical method of B12 supplementation.
Each 3-spray dose contains 1000 mcg of methylcobalamin and adenosylcobalamin. Sublingual administration allows for rapid absorption through the oral mucosa.
⭐ Benefits:
- Bypasses the digestive tract — ideal for those with gastrointestinal issues, elderly individuals, or those following a vegetarian/vegan diet
- Provides active forms of B12 directly — no need for conversion in the liver
- Convenient and user-friendly — no injections or large tablets required
A study by Sharabi et al. (2003) demonstrated that sublingual absorption of methylcobalamin spray is comparable to intramuscular injection.
Recommended For:
- Fatigue, brain fog, cognitive difficulties
- Chronic or subclinical B12 deficiency
- Vegan/vegetarian diet
- Hypothyroidism or metabolic disorders
- Periods of high physical or mental stress
